Functional condition of microcirculation in the zone of intestinal anastomosis during postoperative period upon stimulation of its regeneration (experimental study)

Objectives: to conduct a comparative assessment of the functional condition microcirculation digestive anastomosis zone in early and delayed postoperative period upon local usage autogenic growth factors (PRP). The experiment was performed on 30 mature laboratory rabbits. All animals underwent imposition two "end-to-end" intestinal anastomosis: control one at distance 15 cm from ileocecal angle experimental retreating imposed anastomosis. differed by using method stimulation its regeneration via injecting platelet-riched-plasm A state carried out 3rd, 7th, 14th days laser doppler flowmetry (LDF). obtained data determined ability PRP improve conditions regenerative process increasing rate basal blood flow tissue perfusion, rates which have maximum values (3 day).